Glossary entry (derived from question below)
English term or phrase:
alpha adjustment
Polish translation:
korekta poziomu istotności
Added to glossary by
Polangmar
Oct 26, 2011 02:13
12 yrs ago
8 viewers *
English term
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alpha adjustment
English to Polish
Medical
Mathematics & Statistics
Opis metod statystycznych projektu badania klinicznego. Zdanie:
Alpha adjustment of OS CIs for interim analysis
mile widziane wyjaśnienia nawet bez tłumaczenia, materiały pomocnicze, linki, itp.
Alpha adjustment of OS CIs for interim analysis
mile widziane wyjaśnienia nawet bez tłumaczenia, materiały pomocnicze, linki, itp.
Proposed translations
(Polish)
| 4 | korekta poziomu istotności |
Polangmar
|
References
| alpha adjustment and spending |
M.A.B.
|
Change log
Nov 1, 2011 21:22: Polangmar Created KOG entry
Proposed translations
52 mins
Selected
korekta poziomu istotności
Czyli korekta alfy.
Badania, które prowadzę, dotyczą korekty poziomu istotności uwzględniającej strukturę korelacji pomiędzy statystykami testowymi oraz wyznaczania efektywnej...
http://tinyurl.com/3q8omsx
Badania, które prowadzę, dotyczą korekty poziomu istotności uwzględniającej strukturę korelacji pomiędzy statystykami testowymi oraz wyznaczania efektywnej...
http://tinyurl.com/3q8omsx
4 KudoZ points awarded for this answer.
Reference comments
3 hrs
Reference:
alpha adjustment and spending
http://www2.statistics.com/resources/glossary/a/alphaspfn.ph...
In the interim monitoring of clinical trials, multiple looks are taken at the accruing results. In such circumstances, akin to multiple testing, the alpha-value at each look must be adjusted in order to preserve the overall Type-1 Error. Alpha spending functions, (the Pocock family is one such set; the Lan-Demets spending function a more specific case) establish these adjusted alpha-values for each interim monitoring point, given the overall alpha. Typically, they establish relatively high alpha-values for early looks, and lower alpha-values for later looks. Thus, they constitute "stopping boundaries," which, when crossed, indicate that statistical significance has been established. When graphed, a typical set of stopping boundaries looks like an inverted V pointing to the right. (horizontal axis represents number of events recorded, vertical axis the standardized value of the test statistic.)
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Note added at 5 godz. (2011-10-26 07:44:02 GMT)
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http://en.wikipedia.org/wiki/Multiple_comparisons
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Note added at 5 godz. (2011-10-26 07:45:42 GMT)
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General methods of alpha adjustment for multiple comparisons
Closed testing procedure
Bonferroni correction
Boole–Bonferroni bound
Holm–Bonferroni method
Westfall–Young step-down approach of Westfall and Young
method of Benjamini and Hochberg
Testing hypotheses suggested by the data
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Note added at 5 godz. (2011-10-26 07:55:58 GMT)
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Tu masz świetne źródło: www.biecek.pl/statystykaMedyczna/WielTestHipotez.pdf
Na początku dużo wzorów i teorii, ale ogólnie ładnie opisane o co chodzi.
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Note added at 5 godz. (2011-10-26 07:59:18 GMT)
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http://pol.proz.com/kudoz/english_to_polish/mathematics_stat...
In the interim monitoring of clinical trials, multiple looks are taken at the accruing results. In such circumstances, akin to multiple testing, the alpha-value at each look must be adjusted in order to preserve the overall Type-1 Error. Alpha spending functions, (the Pocock family is one such set; the Lan-Demets spending function a more specific case) establish these adjusted alpha-values for each interim monitoring point, given the overall alpha. Typically, they establish relatively high alpha-values for early looks, and lower alpha-values for later looks. Thus, they constitute "stopping boundaries," which, when crossed, indicate that statistical significance has been established. When graphed, a typical set of stopping boundaries looks like an inverted V pointing to the right. (horizontal axis represents number of events recorded, vertical axis the standardized value of the test statistic.)
--------------------------------------------------
Note added at 5 godz. (2011-10-26 07:44:02 GMT)
--------------------------------------------------
http://en.wikipedia.org/wiki/Multiple_comparisons
--------------------------------------------------
Note added at 5 godz. (2011-10-26 07:45:42 GMT)
--------------------------------------------------
General methods of alpha adjustment for multiple comparisons
Closed testing procedure
Bonferroni correction
Boole–Bonferroni bound
Holm–Bonferroni method
Westfall–Young step-down approach of Westfall and Young
method of Benjamini and Hochberg
Testing hypotheses suggested by the data
--------------------------------------------------
Note added at 5 godz. (2011-10-26 07:55:58 GMT)
--------------------------------------------------
Tu masz świetne źródło: www.biecek.pl/statystykaMedyczna/WielTestHipotez.pdf
Na początku dużo wzorów i teorii, ale ogólnie ładnie opisane o co chodzi.
--------------------------------------------------
Note added at 5 godz. (2011-10-26 07:59:18 GMT)
--------------------------------------------------
http://pol.proz.com/kudoz/english_to_polish/mathematics_stat...
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