English to Russian Medical Medical: Pharmaceuticals

Definitive pneumococcal pneumonia: clinically and radiograph ically confirmed pneumonia with S. pneumoniae isolated from a usually sterile site.
Definitive pneumococcal pneumonia (as defined in A5): of a pneumococcal serotype included in the vaccine administered.
Five studies reported on vaccine-type IPD and four studies reported outcomes on vaccine-type definitive pneumonia.
Definitive pneumococcal pneumonia
PPV reduced the risk of definitive pneumococcal pneumonia, with a pooled estimated OR of 0.26 (95% Cl 0.15 to 0.46; random-effects model).
Definitive PPV (vaccine-types only)
In these trials, there were very few cases of IPD: seven cases of definitive pneumococcal pneumonia from two studies and 44 cases of bacter- aemia from six studies (most of which were among HIV-infected adults in Uganda).
Comparison 1 RCTs of vaccination versus placebo, Outcome 5 Definitive pneumococcal pneumonia.
5 Definitive pneumococcal pneumonia