English to French Science Biology (-tech,-chem,micro-) Biosensor based on a tethered particle

contexte
" The present invention relates generally to a biosensor technique based on detecting the presence of an analyte based on changes in motion of a particle attached by a tether to (tethered to) a surface."

"The tethered particle motion (TPM) technique is based on measurements of the motion of particles tethered to a surface, where TPM experiments are reported on proteins that bind to a DNA tether, in order to reveal how the proteins change the DNA conformation. In such studies, measures are taken to avoid not-via-the-tether binding of the particle to the surface, because a particle that is bound to the surface in another way than via the tether, does not give information about the tether"

"A biosensor device for sensing an analyte using tethered particle motion, the biosensor device having a surface and a tether molecule bound at a first end to the surface and bound at a second end to a particle to form a tethered particle, wherein the particle or the surface is functionalized with an analyte-binding moiety"