Glossary entry

English term or phrase:

dopa-release therapy

English answer:

forms of therapy that involve dopamine release / dopamine release as a result of certain therapies

Added to glossary by John Alphonse (X)
Nov 2, 2012 11:22
11 yrs ago
English term

dopa-release therapy

English Medical Medical (general) Parkinson's disease
This term in written in English in the source Italian, but I'm not able to verify if this is actually the correct phrasing in English. The term appears in a paragraph summarizing the results of a clinical trial on a particular drug, but unfortunately both the name of the drug and any other identifying information have been redacted from my source text. The context is that patients under treatment with "dopa-release therapy" have been found to have disorders relating to impulse control.
Change log

Nov 2, 2012 12:52: philgoddard changed "Language pair" from "Italian to English" to "English"

Nov 5, 2012 00:27: John Alphonse (X) Created KOG entry

Responses

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forms of therapy that involve dopamine release / dopamine release as a result of certain therapies

could be referred to as dopa-release therapy/therapies i suppose... not sure it's a direct form of therapy in and of itself...
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4 KudoZ points awarded for this answer.
1 hr

terapia rilascio-dopa

l-dopa is a chemical which is synthesised in our bodies from an organic amino acid tyrosine, a precursor to a neurotransmitter dopamine. dopa can be also found in mucuna pruriens. L dopa has been used in the past with varying degree of success with Alzheimer's patients. An excess of dopamine can lead to agitation and impulsive behaviour. There is actually a quite good film about l-dopa called 'Awakenings'. Of the caveat with l dopa is carboxylation, that's why it is standard clinical practice to co-administer (with L-DOPA) a peripheral DOPA decarboxylase inhibitor.

Now, it seems to me that said 'dopa-release' therapy is centred around the notion that for best results one will have to get a gradual release of l-dopa in their system.
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